Le Grand Sérum
Experience transformative benefits with this premium serum. It diminishes the appearance of fine lines and wrinkles while promoting firmer skin. Features peptide for targeted treatment benefits. Suitable for incorporating into your daily skincare routine.
THE BENEFITS OF CHOOSING US

Description
SKIN SCIENCE
The shortening of telomeres (ends of the chromosomes) is an inevitable phenomenon during the age-related changes of the cells, which can be accelerated by extrinsic external factors such as the sun, tobacco, pollution. However, thanks to telomerase, a protein capable of ensuring the growth and synthesis of telomeres, new units can be recreated at the end of the chromosomes, replacing those that were used and restoring them by adding telomeric DNA. TélomerActiv©, the flagship active ingredient of Le Grand Sérum, enhances the stability and longevity of telomeres to aid prevent the irreversible accumulation of skin cell aging markers. This groundbreaking anti-senescence active ingredient slows down the aging of its cells and increases collagen production.
FORMULA DETAILS
WATER (AQUA), PROPYLENE GLYCOL, GLYCERIN, PROPANEDIOL, MALTODEXTRIN, HYDROLYZED HAZELNUT PROTEIN, LACTOBACILLUS/WASABIA JAPONICA ROOT FERMENT EXTRACT, PENTYLENE GLYCOL, MYRTUS COMMUNIS LEAF EXTRACT, ALLIUM CEPA (ONION) BULB EXTRACT, COMMIPHORA MYRRHA RESIN EXTRACT, HONEY EXTRACT (MEL EXTRACT), CAMELLIA SINENSIS LEAF EXTRACT, HAMAMELIS VIRGINIANA (WITCH HAZEL) BARK/LEAF EXTRACT, CENTELLA ASIATICA EXTRACT, HYPERICUM PERFORATUM FLOWER/LEAF/STEM EXTRACT, PUNICA GRANATUM PERICARP EXTRACT, HAEMATOCOCCUS PLUVIALIS EXTRACT, HYDROLYZED SOY PROTEIN, HYDROLYZED YEAST PROTEIN, YEAST EXTRACT, SACCHAROMYCES CEREVISIAE EXTRACT, BIOSACCHARIDE GUM-1, ACETYL HEXAPEPTIDE-8, NIACINAMIDE, SODIUM HYALURONATE, LACTIC ACID, SODIUM LACTATE, CITRIC ACID, ALLANTOIN, SERINE, ROYAL JELLY EXTRACT, CARUM CARVI (CARAWAY) SEED OIL, MENTHA PIPERITA (PEPPERMINT) OIL, ACACIA SENEGAL GUM, XANTHAN GUM, CARAMEL, SORBITOL, LECITHIN, 1,2-HEXANEDIOL, TEA-LACTATE, UREA, PHENYLPROPANOL, PHENOXYETHANOL, CAPRYLYL GLYCOL, SODIUM BENZOATE, POTASSIUM SORBATE, LIMONENE. Warning: the lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche formulation, please read the list of ingredients on its packaging to ensure that the ingredients are suitable for your personal use. In case of an allergy, please consult.
HOW TO USE
Apply 4 to 5 drops of finishing serum to the entire face, neck and décolleté, in the morning and/or at night This solution is applied as the final touch of the Biologique Recherche skincare program Avoid contact with eyes. For external use only.
Additional information
| size | 30ml, 8ml |
|---|---|
| Concern | Anti-aging, Antioxidant support, UV protection |
| Special Labels | DERMATOLOGIST-APPROVED |
79 reviews for Le Grand Sérum
Quick Comparison
| Le Grand Sérum remove | Sérum Matriciel Visage remove | Black Diamond Contour Gel remove | Dermopore remove | Sérum PIGM 400 remove | Black Diamond Vitamin C Brightening Booster remove | |||||||||||||||||||||||||||||||||||
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| Name | Le Grand Sérum remove | Sérum Matriciel Visage remove | Black Diamond Contour Gel remove | Dermopore remove | Sérum PIGM 400 remove | Black Diamond Vitamin C Brightening Booster remove | ||||||||||||||||||||||||||||||||||
| Image | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ||||||||||||||||||||||||||||||||||
| SKU | GRASRU544 | SRUMATVI538 | BLADIACO003 | DERXXX535 | SRUPIG537 | BLADIAVI044 | ||||||||||||||||||||||||||||||||||
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| Price | Original price was: 250.00€.180.00€Current price is: 180.00€. | Original price was: 165.00€.118.00€Current price is: 118.00€. | Original price was: 155.00€.108.00€Current price is: 108.00€. | |||||||||||||||||||||||||||||||||||||
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| Description | Experience transformative benefits with this premium serum. It diminishes the appearance of fine lines and wrinkles while promoting firmer skin. Features peptide for targeted treatment benefits. Suitable for incorporating into your daily skincare routine. | A powerful serum formulated for optimal skin health. It diminishes the appearance of fine lines and wrinkles while promoting firmer skin. Infused with peptide for optimal skin nourishment. Suitable for incorporating into your daily skincare routine. | This luxurious contour gel delivers professional-grade results. Enriched with diamond for enhanced effectiveness. Perfect for maintaining healthy, vibrant-looking skin. | A sophisticated treatment for visible skin improvement. Targets visible signs of aging for a more youthful, refined complexion. Perfect for maintaining healthy, vibrant-looking skin. | Experience transformative benefits with this premium serum. It diminishes the appearance of fine lines and wrinkles while promoting firmer skin. Addresses pigmentation concerns for more balanced skin tone. A natural formula solution for discerning skincare enthusiasts. | This advanced skincare formula addresses multiple concerns. Illuminates dull skin and restores natural radiance. Works to minimize dark spots and promote uniform complexion. Powered by vitamin c to deliver superior results. | ||||||||||||||||||||||||||||||||||
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Sophia C. –
using this for a month now. no more flaking and sun exposure dryness healed. dryness eliminated completely.
Amelia U. –
my décolletage was frustrating. tried this after seeing recommendations. first week was subtle but by week 3 i noticed moisture retention improved and hydration restored in six weeks. after 8 weeks peeling skin resolved. also intense hydration works and comfortable all day. now air conditioning no longer dries skin and plump hydrated skin. hydration sustained. will definitely repurchase. hype is real. 5/10!!
Charlotte Z. –
nothing else compares. desert climate skin thriving also retinol dryness prevented!!
Sophia S. –
moisture sealed in and hydration restored in three weeks but barrier repair visible. mind blown!
Sophia V. –
struggled with hormonal chaos forever. finally found this product. first week was subtle but by week 3 I noticed moisture retention all day and seasonal dryness eliminated. after 2 months dryness under control. screaming. also post-cleanse comfort achieved and peeling skin resolved. now exfoliation dryness avoided and desert climate skin thriving. comfortable all day. so happy I tried this
Isabella S. –
comfortable all day also cracked skin healed. everyone needs this.
Sophia Z. –
exfoliation dryness avoided but hormonal dryness balanced
Emma V. –
dry skin repaired. skin stays hydrated all day
Emma L. –
breakout cycle broken but clearer skin achieved also no more painful under-skin bumps
Sophia E. –
honestly impressed with this. dryness disappeared and airplane skin stays hydrated. skin stays hydrated all day. also dry skin transformed!
Mia I. –
struggled with remembers old versions forever. decided to give this a shot. first week was subtle but by week 3 I noticed heated room dryness prevented and dry areas healed. after 6 weeks dry skin repaired. also mature skin dryness addressed and swimming dryness prevented. now chronic dryness finally resolved and chlorine damage reversed. comfortable all day. will definitely repurchase. thrilled.
Charlotte Y. –
desert climate skin thriving but hydration breakthrough. blessed.
Sophia P. –
struggled with monthly changes forever. finally found this product. first week was subtle but by week 3 I noticed winter dryness conquered completely and moisture sealed in. after 2 months medication-induced dryness helped. also moisture retention improved and desert climate skin thriving. never going back. now swimming dryness prevented and hydrated throughout day. moisture barrier repaired. totally recommend this.
Charlotte C. –
dealing with healing skin for way too long. finally found this product. first week was subtle but by week 3 I noticed peeling skin resolved and dryness problem solved. after 8 weeks moisture balance restored. also deep hydration achieved and hydration maintained. now dry skin fixed completely and dry skin rescued. eczema-related dryness improved. will definitely repurchase. immaculate
Olivia Q. –
using this for 3 weeks now. plump hydrated skin and hydration restored in two weeks. cracked skin healed. need this. also shower-proof hydration!
Emma M. –
no more flaking. dehydration lines plumped and hydration breakthrough. tbh. 10/10!
Charlotte D. –
dry skin rescued also moisture sealed in. skin feels comfortable. 10/10.
Sophia E. –
struggled with texture reliant forever. finally found this product. first week was subtle but by week 3 I noticed hormonal texture changes reversed and smooth skin achieved. after 2 months winter texture problems solved. also texture breakthrough and skin smoothness perfect. now bumps disappeared and skin feels incredible. textured skin cleared. will definitely repurchase. 10/10
Isabella W. –
seasonal dryness eliminated and hydration maintained but dryness eliminated.
Amelia X. –
worth the hype. chronic dryness finally resolved also hydration restored in four months.
Olivia R. –
honestly impressed with this. eczema redness controlled and no more red blotchy patches. cop this. sensitive skin calmed. also perioral redness cleared.
Mia Y. –
dealing with expects worst for years. decided to give this a shot. first week was subtle but by week 3 I noticed medication-induced dryness helped and dry patches healed. after 6 weeks moisture sealed in. also rough dry patches smoothed and dryness disappeared. now deep hydration achieved and moisture barrier repaired. moisture balance restored. totally recommend this. works better than prescription!
Amelia B. –
my dark spots was terrible. tried this after seeing recommendations. first week was subtle but by week 3 I noticed no more flaking and deep hydration achieved. after 8 weeks desert climate skin thriving. also dryness under control and skin drinks it up. now comfortable all day and swimming dryness prevented. chlorine damage reversed. so happy I tried this. drugstore price luxury results
Mia L. –
air conditioning no longer dries skin and seasonal dryness eliminated also dryness concerns gone
Olivia X. –
i understand now. cracked skin healed also hydration sustained but nighttime dryness prevented.
Charlotte I. –
plump hydrated skin but airplane skin stays hydrated also comfortable all day
Michael M. –
HG status. moisture locked in also dry skin transformed but dry skin rescued.
Mia S. –
cracked skin healed also airplane skin stays hydrated and dry skin fixed completely.
Michael X. –
nighttime dryness prevented also plump hydrated skin and skin drinks moisture now. fire!!!
Mia H. –
barrier repair visible but dryness problem solved also dryness eliminated completely!
Sophia A. –
desert climate skin thriving but seasonal dryness eliminated and dryness disappeared.
Olivia G. –
airplane skin stays hydrated but dryness under control. comfortable all day. cant even. 10/10
Olivia D. –
struggled with trust issues forever. finally found this product. first week was subtle but by week 3 I noticed comfortable all day and moisture retention improved. after 8 weeks hydration maintained. also intense hydration works and dehydration lines plumped. now sun exposure dryness healed and no more flaking. chlorine damage reversed. best purchase in a while. 9/10.
Olivia Y. –
sun exposure dryness healed and dry skin repaired. tears of joy
Amelia M. –
plump hydrated skin but dryness problem solved!!
Amelia B. –
honestly impressed with this. barrier repair visible and chronic dryness finally resolved. must have. moisture retention improved. also sun exposure dryness healed.
Mia N. –
skin quenched completely but moisture levels perfect. 9/10!!!
Emma I. –
eczema-related dryness improved. dryness eliminated
Amelia L. –
im dead. texture issues resolved. smooth finish achieved
Mia Z. –
moisture sealed in. dry patches gone.
Isabella I. –
dryness eliminated also dryness disappeared. hydrated feeling lasts!
Sophia A. –
struggled with maskne forever. finally found this product. first week was subtle but by week 3 I noticed moisture levels perfect and flaky patches history. after 2 months moisture barrier repaired. also comfortable all day and dry skin transformed. now seasonal dryness eliminated and rough dry patches smoothed. hydrated throughout day. totally recommend this. nothing else worked.
Mia U. –
worth the hype. deep hydration achieved and dry skin transformed.
Olivia C. –
struggled with dry patches forever. finally found this product. first week was subtle but by week 3 I noticed dry patches gone and eczema-related dryness improved. after 2 months hydrated throughout day. also air conditioning no longer dries skin and dry areas healed. now dry skin rescued and chlorine damage reversed. moisture barrier repaired. best purchase in a while. 10/10.
Mia L. –
using this for a month now. rough dry patches smoothed and moisture balance restored. moisture locked in. also winter dryness conquered completely
Isabella H. –
dealing with salt air for way too long. finally found this product. first week was subtle but by week 3 I noticed dryness problem solved and tight skin feeling eliminated. after 8 weeks hydrated feeling lasts. also moisture sealed in and dry patches healed. now eczema-related dryness improved and air conditioning no longer dries skin. retinol dryness prevented. so happy I tried this.
Harper Y. –
using this for a month now. moisture levels perfect and plump hydrated skin. dryness problem solved. also moisture balance restored. fire
Mia E. –
chronic dryness finally resolved and dry patches healed and dryness concerns gone.
Emma S. –
plump and glowing. psoriasis dryness managed but skin feels comfortable
Charlotte X. –
dryness concerns gone and moisture balance restored but skin feels hydrated. finally.
Sophia K. –
after 3 weeks of use. dryness eliminated and post-cleanse comfort achieved. chronic dryness finally resolved.
James G. –
struggled with analytical forever. kicking myself. decided to give this a shot. first week was subtle but by week 3 I noticed skin stays hydrated all day and heated room dryness prevented. after 8 weeks moisture locked in. also hydration maintained and peeling skin resolved. now nighttime dryness prevented and swimming dryness prevented. skin quenched completely. best purchase in a while.
Sophia Z. –
morning dryness gone and swimming dryness prevented!!!
Sophia T. –
dry skin rescued but swimming dryness prevented. top tier.
Olivia N. –
after 2 weeks of use. rough skin healed and sandpaper feeling eliminated. professional-level results at home. actually works.
James F. –
using this for 3 weeks now. dryness disappeared and psoriasis dryness managed. dry skin transformed. spreading the word. 8/10.
Amelia Y. –
after a month of use. tight skin feeling eliminated and hydration maintained. on my 5th tube. rough dry patches smoothed
Amelia P. –
really happy with the results. cracked skin healed and no more flaking. hydration sustained.
Olivia V. –
shower-proof hydration but rough dry patches smoothed
Emma G. –
after a month of use. exfoliation dryness avoided and chronic dryness finally resolved. plump hydrated skin. also skin drinks moisture now!
Mia Z. –
sun exposure dryness healed but desert climate skin thriving.
Harper G. –
after 2 weeks of use. medication-induced dryness helped and hydration sustained. dermatologist approved. moisture balance restored. 10/10.
Olivia Y. –
my perfect skin goal was exhausting. finally found this product. first week was subtle but by week 3 I noticed hydration breakthrough and intense hydration works. after 2 months psoriasis dryness managed. also skin feels comfortable and mature skin dryness addressed. now dryness concerns gone and moisture levels perfect. shower-proof hydration. so happy I tried this!
Amelia P. –
dealing with late nights for quite some time. finally found this product. first week was subtle but by week 3 I noticed airplane skin stays hydrated and moisture retention all day. after 6 weeks heated room dryness prevented. also dryness under control and moisture sealed in. now comfortable all day and hydrated throughout day. dryness eliminated. so happy I tried this. drugstore price luxury results.
Emma X. –
dermatologist-approved results. sensitive skin protected but hot flash redness minimized. kicking myself
Emma M. –
my prevention was frustrating. tried this after reading reviews. first week was subtle but by week 3 I noticed plump hydrated skin and hydrated feeling lasts. after 2 months medication-induced dryness helped. also skin feels comfortable and skin quenched completely. now dry skin fixed completely and seasonal dryness eliminated. dry patches gone. i cant. best purchase in a while.
Mia Y. –
hormonal dryness balanced. dryness problem solved but moisture retention all day.
Olivia A. –
flaky patches history and moisture retention improved also airplane skin stays hydrated.
Charlotte W. –
dealing with décolletage for years. tried this after reading reviews. first week was subtle but by week 3 I noticed tight skin feeling eliminated and dryness under control. after 6 weeks flaky patches history. also dry skin transformed and moisture sealed in. now skin feels comfortable and nighttime dryness prevented. skin feels hydrated. best purchase in a while. legit works. 10/10.
James Y. –
cant believe. dryness disappeared also chronic dryness finally resolved and post-cleanse comfort achieved
Charlotte I. –
cracked skin healed. air conditioning no longer dries skin. 8/10!
Emma H. –
dry skin rescued but exfoliation dryness avoided
Emma Q. –
bumpy forehead texture cleared. orange peel texture minimized
Harper Q. –
deadass. tight skin feeling eliminated also flaky patches history. 10/10!
Mia C. –
cracked skin healed but barrier repair visible and chlorine damage reversed. highly recommend
Sophia H. –
after a month of use. plump and glowing. medication-induced dryness helped and dry patches healed. winter dryness conquered completely.
Amelia P. –
medication-induced dryness helped. hydration restored in six months and hydrated throughout day.
Mia B. –
cant believe. dryness eliminated completely. retinol dryness prevented. skin drinks it up
Isabella R. –
love this. hydration sustained. tight skin feeling eliminated. dry skin rescued.